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Gene Expression Data
Assay Details
Assay
Reference: J:190417 Rama N, et al., Amyloid precursor protein regulates netrin-1-mediated commissural axon outgrowth. J Biol Chem. 2012 Aug 24;287(35):30014-23
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6681823
Gene symbol: App
Gene name: amyloid beta precursor protein
Antibody: anti-APP clone Y188 (ab32136)
Detection system: Alexa Fluor 488
Results
Specimen 1B WT: embryonic day 11.5 (more )
Note: Double labeled: green - App; red - Dcc (assay MGI:6681824).
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 1B WT anti-APP , 1B WT Merge inset , 1B WT Merge Expression in enriched in commissural axon tracts, colocalized with that of Dcc.
Specimen 1B APP-/-: embryonic day 11.5; Apptm2Cwe/Apptm2Cwe (more )
Note: Double labeled: green - App; red - Dcc (assay MGI:6681824).
Structure Level Pattern Image Note
TS19: future spinal cord Absent 1B APP-/- anti-APP , 1B APP-/- Merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory