Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Aplnrem1(dre/ERT2)Smoc
Name:	apelin receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6514761
Synonyms:	Aplnr-DreER, Aplnrem1(2A-DreERT2)Smoc
Gene:	Aplnr  Location: Chr2:84966704-84970267 bp, + strand  Genetic Position: Chr2, 49.45 cM, cytoband E1
Alliance:	Aplnrem1(dre/ERT2)Smoc page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Aplnrem1(dre/ERT2)Smoc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Aplnr (MGI:1346086)   Mutation details: A 2A-DreERT2-SV40polyA coexpression cassette is inserted before the stop codon of the mouse Aplnr gene via homologous recombination to establish a tamoxifen-inducible Aplnr-DreERT2 tool stain. (J:238766, J:304636)

Activity:	Tissue activity of this recombinase allele
Driver:	Aplnr (mouse) Summary of all recombinase alleles driven by Aplnr. Alliance mouse Aplnr gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aplnr Mutation:	28 strains or lines available

Original:	J:304636 Han X, et al., A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell. 2021 Feb 2;
All:	2 reference(s)