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Gene Expression Data
Assay Details
Assay
Reference: J:96395 Lee S, et al., Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth. Hum Mol Genet. 2005 Mar 1;14(5):627-37
Assay type: RNA in situ
MGI Accession ID: MGI:6514721
Gene symbol: Sim1
Gene name: single-minded family bHLH transcription factor 1
Probe: Sim1 probe17
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: hypothalamus Present 6F
TS21: zona limitans intrathalamica Present 6F
Specimen 6F': embryonic day 12.5; Ndntm2Stw/Ndn+ (more )
Note: Specimen carried a paternally inherited necdin deficiency and was functionally necdin null.
Structure Level Pattern Image Note
TS21: hypothalamus Present 6F' Expression in the necdin null embryo was comparable to control.
TS21: zona limitans intrathalamica Present 6F' Expression in the necdin null embryo was comparable to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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