Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:161880
Bergman JE, et al., Study of smell and reproductive organs in a mouse model for CHARGE syndrome. Eur J Hum Genet. 2010 Feb;18(2):171-7
|
Assay type:
|
Immunohistochemistry
|
MGI Accession ID:
|
MGI:6512844
|
Gene symbol:
|
Gnrh1
|
Gene name:
|
gonadotropin releasing hormone 1
|
|
Results
|
Specimen
5a:
postnatal adult
(more )
Specimen
5a:
(close )
Genetic Background:
|
C3HeB/FeJ
|
Age:
|
postnatal adult
|
Sex:
|
Male
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: diencephalon |
Present |
Regionally restricted |
5a
|
Expression is in the organum vasculosum of the lamina terminalis with fibers extending to the median eminence.
|
TS28: median eminence |
Present |
|
5a
|
|
Specimen
5b:
postnatal adult; Chd7Whi/Chd7 +
(more )
Specimen
5b:
(close )
Genetic Background:
|
C3HeB/FeJ-Chd7Whi
|
Mutant Allele(s):
|
Chd7Whi/Chd7+
|
Age:
|
postnatal adult
|
Sex:
|
Male
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: diencephalon |
Present |
Regionally restricted |
5b
|
Expression is in the organum vasculosum of the lamina terminalis with fibers extending to the median eminence.
|
TS28: median eminence |
Present |
|
|
|
Specimen
5c:
postnatal adult
(more )
Specimen
5c:
(close )
Genetic Background:
|
C3HeB/FeJ
|
Age:
|
postnatal adult
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: diencephalon |
Present |
Regionally restricted |
5c
|
Expression is in the organum vasculosum of the lamina terminalis with fibers extending to the median eminence.
|
TS28: median eminence |
Present |
|
5c
|
|
Specimen
5d:
postnatal adult; Chd7Whi/Chd7 +
(more )
Specimen
5d:
(close )
Genetic Background:
|
C3HeB/FeJ-Chd7Whi
|
Mutant Allele(s):
|
Chd7Whi/Chd7+
|
Age:
|
postnatal adult
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: diencephalon |
Present |
Regionally restricted |
5d
|
Expression is in the organum vasculosum of the lamina terminalis with fibers extending to the median eminence.
|
TS28: median eminence |
Present |
|
5d
|
|
Specimen
5e:
postnatal adult
(more )
Specimen
5e:
(close )
Genetic Background:
|
C3HeB/FeJ
|
Age:
|
postnatal adult
|
Sex:
|
Male
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Specimen
5f:
postnatal adult; Chd7Whi/Chd7 +
(more )
Specimen
5f:
(close )
Genetic Background:
|
C3HeB/FeJ-Chd7Whi
|
Mutant Allele(s):
|
Chd7Whi/Chd7+
|
Age:
|
postnatal adult
|
Sex:
|
Male
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Specimen
5g:
postnatal adult
(more )
Specimen
5g:
(close )
Genetic Background:
|
C3HeB/FeJ
|
Age:
|
postnatal adult
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Specimen
5h:
postnatal adult; Chd7Whi/Chd7 +
(more )
Specimen
5h:
(close )
Genetic Background:
|
C3HeB/FeJ-Chd7Whi
|
Mutant Allele(s):
|
Chd7Whi/Chd7+
|
Age:
|
postnatal adult
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: median eminence |
Present |
|
5h
|
The expression in this heterozygote is reduced compared to wild-type.
|
Specimen
S1a:
embryonic day 16.5
(more )
Specimen
S1a:
(close )
Genetic Background:
|
C3HeB/FeJ
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: nose |
Present |
Regionally restricted |
S1a
|
Expression is in migrating neurons alongside the nasal septum.
|
Specimen
S1b:
embryonic day 16.5; Chd7Whi/Chd7 +
(more )
Specimen
S1b:
(close )
Genetic Background:
|
C3HeB/FeJ-Chd7Whi
|
Mutant Allele(s):
|
Chd7Whi/Chd7+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: nose |
Present |
Regionally restricted |
S1b
|
Expression in this heterozygote is the same as in wild-type.
|
Specimen
S1c:
embryonic day 16.5
(more )
Specimen
S1c:
(close )
Genetic Background:
|
C3HeB/FeJ
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Specimen
S1d:
embryonic day 16.5; Chd7Whi/Chd7 +
(more )
Specimen
S1d:
(close )
Genetic Background:
|
C3HeB/FeJ-Chd7Whi
|
Mutant Allele(s):
|
Chd7Whi/Chd7+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: main olfactory bulb |
Present |
|
S1d
|
Expression in this heterozygote is the same as in wild-type.
|
Specimen
S1e:
embryonic day 16.5
(more )
Specimen
S1e:
(close )
Genetic Background:
|
C3HeB/FeJ
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Specimen
S1f:
embryonic day 16.5; Chd7Whi/Chd7 +
(more )
Specimen
S1f:
(close )
Genetic Background:
|
C3HeB/FeJ-Chd7Whi
|
Mutant Allele(s):
|
Chd7Whi/Chd7+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
10% Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: hypothalamus |
Present |
|
S1f
|
Expression in this heterozygote is the same as in wild-type.
|
|