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Gene Expression Data
Assay Details
Assay
Reference: J:175386 Maier H, et al., Normal fur development and sebum production depends on fatty acid 2-hydroxylase expression in sebaceous glands. J Biol Chem. 2011 Jul 22;286(29):25922-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6512411
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki-67
Detection system: Cy3
Results
Specimen 8C Ki67 +/+: postnatal day 10 (more )
Note: Double labeled: green - Mki67; red - Fa2h (assay MGI:6512407).
Structure Level Pattern Image Note
TS28: sebaceous gland Present 8C +/+ merge , 8C +/+ Ki67
TS28: vibrissa outer root sheath Present 8C +/+ Ki67 , 8C +/+ merge
Specimen 8C Ki67 -/-: postnatal day 10; Fa2htm1Meck/Fa2htm1Meck (more )
Note: Double labeled: green - Mki67; red - Fa2h (assay MGI:6512407).
Structure Level Pattern Image Note
TS28: sebaceous gland Present Regionally restricted 8C -/- Ki67 , 8C -/- merge Elevated numbers of proliferating undifferentiated sebocytes in basal layer of sebaceous gland.
TS28: vibrissa outer root sheath Present Regionally restricted 8C -/- merge , 8C -/- Ki67 Expression in increased numbers of cells in upper outer root sheath.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory