Fev RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:116706 Zhao ZQ, et al., Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity. J Neurosci. 2006 Dec 6;26(49):12781-8
Assay type:	RNA in situ
MGI Accession ID:	MGI:6512031
Gene symbol:	Fev
Gene name:	FEV transcription factor, ETS family member

Probe:	Pet1 probe
Probe preparation:	Antisense RNA

Results

2I ©

Specimen 2I: embryonic day 11.5 (more

)
Note: rostral part of the hindbrain

Structure	Level	Pattern	Image	Note
TS19: hindbrain	Present		2I	Expressed in 5-HT neurons in the rostral part.

2J ©

Specimen 2J: embryonic day 11.5; Lmx1b^tm1Zfc/Lmx1b^tm1Zfc, Tg(Fev-cre)1Esd/0 (more

)
Note: Conditional mutant. rostral part of the hindbrain

Structure	Level	Pattern	Image	Note
TS19: hindbrain	Present		2J	Similar expression patterns in 5-HT neurons in the rostral part, compared with wild-type mice.

Specimen not shown: embryonic day 11.5 (more

)
Note: caudal part of the hindbrain

Structure	Level	Pattern	Image	Note
TS19: hindbrain	Present			Expressed in the caudal part.

Specimen not shown: embryonic day 11.5; Lmx1b^tm1Zfc/Lmx1b^tm1Zfc, Tg(Fev-cre)1Esd/0 (more

)
Note: Conditional mutant. caudal part of the hindbrain

Structure	Level	Pattern	Image	Note
TS19: hindbrain	Present			Similar expression patterns in the caudal part compared with wild-type mice.

3O ©

Specimen 3O: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: hindbrain	Present		3O

3P ©

Specimen 3P: embryonic day 14.5; Lmx1b^tm1Zfc/Lmx1b^tm1Zfc, Tg(Fev-cre)1Esd/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: hindbrain	Present		3P	Highly reduced expression compared with the wild-type.

Specimen not shown: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: hindbrain	Present

Specimen not shown: embryonic day 16.5; Lmx1b^tm1Zfc/Lmx1b^tm1Zfc, Tg(Fev-cre)1Esd/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: hindbrain	Trace			Rarely detected in the mutant.

Specimen not shown: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: raphe nucleus	Present

Specimen not shown: postnatal adult; Lmx1b^tm1Zfc/Lmx1b^tm1Zfc, Tg(Fev-cre)1Esd/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: raphe nucleus	Trace			Virtually absent in the mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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