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Gene Expression Data
Assay Details
Assay
Reference: J:116706 Zhao ZQ, et al., Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity. J Neurosci. 2006 Dec 6;26(49):12781-8
Assay type: RNA in situ
MGI Accession ID: MGI:6512029
Gene symbol: Slc6a4
Gene name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Probe: Sert probe3
Probe preparation: Antisense RNA
Results
Specimen 2E: embryonic day 11.0 (more )
Note: rostral part of the hindbrain
Structure Level Pattern Image Note
TS18: hindbrain Present Regionally restricted 2E Expressed in 5-HT neurons in the rostral part.
Specimen 2F: embryonic day 11.0; Lmx1btm1Zfc/Lmx1btm1Zfc, Tg(Fev-cre)1Esd/0 (more )
Note: Conditional mutant. rostral part of the hindbrain
Structure Level Pattern Image Note
TS18: hindbrain Present Regionally restricted 2F Similar expression patterns in 5-HT neurons in the rostral part, compared with wild-type mice.
Specimen not shown: embryonic day 11.0 (more )
Note: caudal part of the hindbrain
Structure Level Pattern Image Note
TS18: hindbrain Present Expressed in the caudal part.
Specimen not shown: embryonic day 11.0; Lmx1btm1Zfc/Lmx1btm1Zfc, Tg(Fev-cre)1Esd/0 (more )
Note: Conditional mutant. caudal part of the hindbrain
Structure Level Pattern Image Note
TS18: hindbrain Present Similar expression patterns in the caudal part compared with wild-type mice.
Specimen 3G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3G Expressed in 5-HT neurons in the rostral part.
Specimen 3H: embryonic day 12.5; Lmx1btm1Zfc/Lmx1btm1Zfc, Tg(Fev-cre)1Esd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hindbrain Trace Single cells 3H Expression was virtually lost in the mutant, only a few remaining positive cells.
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: raphe nucleus Present
Specimen not shown: postnatal adult; Lmx1btm1Zfc/Lmx1btm1Zfc, Tg(Fev-cre)1Esd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: raphe nucleus Trace Virtually absent in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory