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Gene Expression Data
Assay Details
Assay
Reference: J:157050 Bojanic DD, et al., Differential expression and function of ABCG1 and ABCG4 during development and aging. J Lipid Res. 2010 Jan;51(1):169-81
Assay type: RT-PCR
MGI Accession ID: MGI:6510249
Gene symbol: Cyp46a1
Gene name: cytochrome P450, family 46, subfamily a, polypeptide 1
Probe: Cyp46a1-pC, Cyp46a1-pD
Probe preparation: labelled with SYBR green
Assay notes: Quantitative real-time PCR. Relative expression is shown normalized to Gapdh.
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
WT 2MO P m 2 TS28: brain Present 1 µg; total RNA Not Specified Not Specified
DKO 2 MO P m 2 TS28: brain Present (a) 1 µg; total RNA involves: 129P2/OlaHsd * C57BL/6 Abcg1tm1Dgen/Abcg1tm1Dgen, Abcg4tm1Dgen/Abcg4tm1DgenNot Specified
WT 7MO P m 7 TS28: brain Present 1 µg; total RNA Not Specified Not Specified
DKO 7MO P m 7 TS28: brain Present (b) 1 µg; total RNA involves: 129P2/OlaHsd * C57BL/6 Abcg1tm1Dgen/Abcg1tm1Dgen, Abcg4tm1Dgen/Abcg4tm1DgenNot Specified
Notes:
(a) Expression in this mutant is the same as in wild-type.
(b) Expression increased significantly by 7 months in this mutant compared to wild-type.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory