About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:37194 Thomas P, et al., Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo. Curr Biol. 1996 Nov 1;6(11):1487-96
Assay type: RNA in situ
MGI Accession ID: MGI:6509302
Gene symbol: Hesx1
Gene name: homeobox gene expressed in ES cells
Probe: Hesx1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1a: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo endoderm Present Regionally restricted 1a Expressed in a small patch of cells (10-20 cells) in the anterior midline. This region was separated from the extraembryonic-embryonic junction by approximately five endoderm cell diameters.

Specimen 1b: embryonic day 6.5 (more )
Note: early-streak stage
Structure Level Pattern Image Note
TS9: embryo endoderm Present Regionally restricted 1b Expression remained restricted to a small patch of endoderm cells during primitive streak elongation.

Specimen 1c: embryonic day 7.0 (more )
Note: late-streak stage
Structure Level Pattern Image Note
TS10: neural ectoderm Weak Regionally restricted 1c Expressed in the prospective neurectoderm immediately adjacent to the hybridizing endoderm domain.
TS10: embryo endoderm Present Regionally restricted 1c Expressed in the anterior endoderm.

Specimen 1d: embryonic day 7.5 (more )
Note: headfold stage
Structure Level Pattern Image Note
TS11: neural ectoderm Present Regionally restricted 1d Expression in the anterior neurectoderm intensified and spread laterally during formation of the cranial neural folds to encompass the developing prosencephalon.

Specimen 1e: embryonic day 7.5 (more )
Note: neural plate stage
Structure Level Pattern Image Note
TS11: neural ectoderm Present Regionally restricted 1e Expression in the anterior neurectoderm intensified and spread laterally during formation of the cranial neural folds to encompass the developing prosencephalon.

Specimen 1f: embryonic day 7.5 (more )
Note: headfold stage
Structure Level Pattern Image Note
TS11: neural ectoderm Present Regionally restricted 1f Expression in the anterior neurectoderm intensified and spread laterally during formation of the cranial neural folds to encompass the developing prosencephalon.

Specimen 1g: embryonic day 6.5 (more )
Note: early-streak stage
Structure Level Pattern Image Note
TS9: embryo endoderm Present Regionally restricted 1g Expression remained restricted to a small patch of endoderm cells during primitive streak elongation.

Specimen 1i: embryonic day 6.5 (more )
Note: Early-streak stage. Also stained for T (assay MGI:6509305).
Structure Level Pattern Image Note
TS9: embryo endoderm Present Regionally restricted 1i Expression remained restricted to a small patch of endoderm cells.

Specimen 1j: embryonic day 7.0 (more )
Note: Midstreak stage. Also stained for T (assay MGI:6509305).
Structure Level Pattern Image Note
TS10: embryo endoderm Present Regionally restricted 1j Expression remained restricted to a small patch of endoderm cells.

Specimen 1k: embryonic day 8.0 (more )
Note: early somite-stage
Structure Level Pattern Image Note
TS12: neural ectoderm Present Regionally restricted 1k Expression in the anterior neurectoderm intensified and spread laterally during formation of the cranial neural folds to encompass the developing prosencephalon.
TS12: future prosencephalon Present 1k

Specimen 1l: embryonic day 8.0 (more )
Note: early somite-stage
Structure Level Pattern Image Note
TS12: foregut diverticulum endoderm Present Regionally restricted 1l Expressed in the midline.
TS12: future prosencephalon neural fold Present 1l
TS12: oral region ectoderm Present 1l

Specimen 1m: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: diencephalon Present Regionally restricted 1m Expressed in the ventral diencephalon.
TS15: oral region ectoderm Present 1m

Specimen 1n: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Present 1n

Specimen 1o: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Present 1o


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory