Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Myh6-DSP*R2834H)#Jato
Name:	transgene insertion, Jeffrey Towbin
MGI ID:	MGI:6509050
Synonyms:	R2834H-Tg
Transgene:	Tg(Myh6-DSP*R2834H)#Jato  Location: unknown
Alliance:	Tg(Myh6-DSP*R2834H)#Jato page

Strain of Origin:

C57BL/6J

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Myh6-DSP*R2834H)#Jato expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human DSP (1832) Dsp  (MGI:109611) Expresses a human cDNA encoding a R2834H variant   Mutation details: The mouse Myh6 promoter drives expression of a mutated human DSP cDNA encoding a R2834H alteration. Expression is detected in the myocardium. (J:125067)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:125067 Yang Z, et al., Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circ Res. 2006 Sep 15;99(6):646-55
All:	3 reference(s)