Gene Expression Data
Assay Details
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Assay
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Reference:
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J:151992
Vanhoutteghem A, et al., Basonuclin 2 has a function in the multiplication of embryonic craniofacial mesenchymal cells and is orthologous to disco proteins. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14432-7
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6509040
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Gene symbol:
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Bnc2
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Gene name:
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basonuclin zinc finger protein 2
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
4I:
(close  )
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Genetic Background:
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involves: C57BL/6 * CBA
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Mutant Allele(s):
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Bnc2Gt(pU21)18Imeg/Bnc2+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Nasal region.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: head mesenchyme |
Present |
Regionally restricted |
4I
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Staining was specific to mesenchymal cells surrounding cartilage.
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Specimen
4J:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Mutant Allele(s):
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Bnc2Gt(pU21)18Imeg/Bnc2+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Nasal region.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: head mesenchyme |
Present |
Regionally restricted |
4J
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Staining was specific to mesenchymal cells surrounding cartilage.
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Specimen
S1A:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Mutant Allele(s):
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Bnc2Gt(pU21)18Imeg/Bnc2+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
S1C:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Mutant Allele(s):
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Bnc2Gt(pU21)18Imeg/Bnc2+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: limb |
Present |
Regionally restricted |
S1C
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Expression was detected around the joints in the anterior limb.
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Specimen
S2A -/-:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: suture |
Strong |
Regionally restricted |
S2A -/-
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High beta-gal activity was detected in the newborn skull, particularly in the sutures and the posterior fontanelle.
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Specimen
S2B:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: secondary palate |
Strong |
Regionally restricted |
S2B -/-
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Strong staining was observed around the palatal cleft.
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Analysis Tools
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