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Gene Expression Data
Assay Details
Assay
Reference: J:251629 Waclaw RR, et al., Foxo1 is a downstream effector of Isl1 in direct pathway striatal projection neuron development within the embryonic mouse telencephalon. Mol Cell Neurosci. 2017 Apr;80:44-51
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6508073
Gene symbol: Ppp1r1b
Gene name: protein phosphatase 1, regulatory inhibitor subunit 1B
Antibody: anti-Darpp-32
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 4C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: corpus striatum Present 4C Expression is in striatal projection neurons.
TS23: cerebral cortex Present 4C
Specimen 4D: embryonic day 15.5; Foxo1tm1Rdp/Foxo1tm1Rdp, Tg(mI56i-cre,EGFP)1Kc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: corpus striatum Present 4D There is a 48% reduction in expression in this mutant compared to controls.
TS23: cerebral cortex Present 4D Expression in this tissue is the same as in controls.
Specimen 5A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: corpus striatum Present 5A
Specimen 5B: embryonic day 18.5; Foxo1tm1Rdp/Foxo1tm1Rdp, Tg(mI56i-cre,EGFP)1Kc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: corpus striatum Present 5B Expression in this mutant is similar to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory