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Gene Expression Data
Assay Details
Assay
Reference: J:251629 Waclaw RR, et al., Foxo1 is a downstream effector of Isl1 in direct pathway striatal projection neuron development within the embryonic mouse telencephalon. Mol Cell Neurosci. 2017 Apr;80:44-51
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6508068
Gene symbol: Foxo1
Gene name: forkhead box O1
Antibody: anti-Foxo1
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: corpus striatum Present 3A
Specimen 3B: embryonic day 15.5; Isl1tm1.1Whk/Isl1tm1.1Whk, Tg(mI56i-cre,EGFP)1Kc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: corpus striatum Trace 3B There is an 85% reduction in staining in this mutant compared to controls.
Specimen 3C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: corpus striatum Present 3C
Specimen 3D: embryonic day 18.5; Isl1tm1.1Whk/Isl1tm1.1Whk, Tg(mI56i-cre,EGFP)1Kc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: corpus striatum Weak 3D There is an 55% reduction in staining in this mutant compared to controls.
Specimen 4A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: corpus striatum Present 4A
TS23: forebrain vascular element Present 4A
TS23: telencephalon Present Regionally restricted 4A Exprerssion is in the dorsomedial telencephalon.
Specimen 4B: embryonic day 15.5; Foxo1tm1Rdp/Foxo1tm1Rdp, Tg(mI56i-cre,EGFP)1Kc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: forebrain vascular element Present 4B Expression in this tissue is the same as in contriols.
TS23: telencephalon Present 4B Expression in this tissue is the same as in contriols.
TS23: corpus striatum Absent 4B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory