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Tg(Cela1-Lta,Cela1-Ltb)58Heizu
Transgene Detail
Summary
Symbol: Tg(Cela1-Lta,Cela1-Ltb)58Heizu
Name: transgene insertion 58, Mathias Heikenwlder
MGI ID: MGI:6506371
Synonyms: Tg(Ela1-Lta,b)
Transgene: Tg(Cela1-Lta,Cela1-Ltb)58Heizu  Location: unknown  
Alliance: Tg(Cela1-Lta,Cela1-Ltb)58Heizu page
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Cela1-Lta,Cela1-Ltb)58Heizu expresses 2 genes
 
Mutation detailsTwo transgenic constructs carrying mouse Lta and Ltb cDNA, respectively, under the control of the rat Cela1 (formerly Ela1) promoter are co-injected into C57BL/N zygotes. Founder lines 40 and 58 were established. Founder 58 is the high-expressing line. Southern blot analysis indicates that 3 copies of the transgene were integrated in the mouse genome. (J:301576)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:301576 Seleznik GM, et al., Lymphotoxin beta receptor signaling promotes development of autoimmune pancreatitis. Gastroenterology. 2012 Nov;143(5):1361-1374
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory