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Gene Expression Data
Assay Details
Assay
Reference: J:179369 Zhang Y, et al., Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity. Genes Dev. 2012 Jan 1;26(1):69-81
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6506179
Gene symbol: Ret
Gene name: ret proto-oncogene
Reporter: GFP
Direct Detection
Results
Specimen 1L: embryonic day 12.5; Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted 1L Expression in enteric neural crest cells (ENCC).
Specimen 1M: embryonic day 12.5; Phactr4humdy/Phactr4humdy, Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS20: stomach Weak Regionally restricted 1M Reduced number of mutant ENCCs.
Specimen 1N: embryonic day 12.5; Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS20: foregut Present Regionally restricted 1N Expression in enteric neural crest cells (ENCC).
Specimen 1O: embryonic day 12.5; Phactr4humdy/Phactr4humdy, Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS20: foregut Weak Regionally restricted 1O Reduced number of mutant ENCCs.
Specimen 1P: embryonic day 12.5; Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS20: midgut Present Regionally restricted 1P Expression in enteric neural crest cells (ENCC).
Specimen 1Q: embryonic day 12.5; Phactr4humdy/Phactr4humdy, Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS20: midgut Weak Regionally restricted 1Q Reduced number of mutant ENCCs.
Specimen 1R: embryonic day 12.5; Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS20: hindgut Present Regionally restricted 1R Expression in enteric neural crest cells (ENCC) to post-caecum hindgut level. Organized network of expressing cells.
Specimen 1S: embryonic day 12.5; Phactr4humdy/Phactr4humdy, Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS20: hindgut Weak Regionally restricted 1S Reduced number of ENCCs. Expressing cells weremore randomly distributed and often appeared as individualized cells.
Specimen S5D: embryonic day 9.5; Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS15: foregut Present Regionally restricted S5D Expression in enteric neural crest cells (ENCC).
Specimen S5E: embryonic day 9.5; Phactr4humdy/Phactr4humdy, Rettm1Jmi/Ret+ (more )
Structure Level Pattern Image Note
TS15: foregut Weak Regionally restricted S5E Reduced number of ENCCs relative to wildtype.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory