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Gene Expression Data
Assay Details
Assay
Reference: J:296649 Lindstrom NO, et al., Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning. J Am Soc Nephrol. 2018 Mar;29(3):825-840
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6505986
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Antibody: anti-Six2 (MBS610128)
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: The authors used two Six2 antibodies; it is possible that MGI:6505815 was used to obtain some or all of these data.
Results
Specimen 1B: embryonic day 15.5 (more )
Note: Triple labeled: red - Six2; green - Lef1 (assay MGI:6505980); blue - Krt8 (assay MGI:6505962)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 1B left Expression is seen in nephrogenic progenitor cells.
Specimen 1D'/S3B': embryonic day 15.5 (more )
Note: Triple labeled: red - Six2; green - Pax8 (assay MGI:6505985); blue - Krt8 (assay MGI:6505962)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 1D' , S3B' Expression is seen in nephrogenic progenitor cells.
Specimen 2C': embryonic day 15.5 (more )
Note: Triple labeled: red - Six2; green - Lef1 (assay MGI:6505980); blue - Krt8 (assay MGI:6505962)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 2C' Expression is seen in nephrogenic progenitor cells.
Specimen 4B - RV: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: renal vesicle Present 4B SIX2 - RV
Specimen 4B - SSB: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: s-shaped body Present 4B SIX2 - SSB
Specimen S1A': embryonic day 15.5 (more )
Note: Triple labeled: green - Six2; red - Cited1 (assay MGI:6505990); blue - Lamb1 (assay MGI:6505972)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted S1A' SIX2 , S1A' Expression is seen in nephrogenic progenitor cells.
Specimen S1C': embryonic day 15.5 (more )
Note: Triple labeled: red - Six2; green - Pax8 (assay MGI:6505985); blue - Krt8 (assay MGI:6505962)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted S1C' , S1C' SIX2/KRT8 Expression is seen in nephrogenic progenitor cells.
Specimen S2 upper: postnatal day 2 (more )
Note: Triple labeled: green - Six2; red - Lef1 (assay MGI:6505980); blue - Krt8 (assay MGI:6505962)
Structure Level Pattern Image Note
TS27: cap mesenchyme Present Regionally restricted S2_upper Expression is seen in nephrogenic progenitor cells.
Specimen S2 lower: postnatal day 2 (more )
Note: Triple labeled: green - Six2; red - Lef1 (assay MGI:6505980); blue - Krt8 (assay MGI:6505962)
Structure Level Pattern Image Note
TS27: cap mesenchyme Present Regionally restricted S2_lower Expression is seen in nephrogenic progenitor cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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