About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:267460 Hrycaj SM, et al., Hox5 genes direct elastin network formation during alveologenesis by regulating myofibroblast adhesion. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10605-E10614
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6505974
Gene symbol: Eln
Gene name: elastin
Results
Specimen 6A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung Present Regionally restricted 6A Expression exclusively around proximal airway through E16.5.
TS24: alveolar system Absent 6A No expression in distal airways.

Specimen 6B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lung Present Regionally restricted 6B Expression in distal lung initiates at E17.5.
TS25: alveolar system Present 6B

Specimen 6C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: alveolar system Present Regionally restricted 6C Elastin network continues to be elaborated over the nest several days. Authors report a complex elastin network in distal lung by E18.5.

Specimen 6D: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: alveolar system Present Regionally restricted 6D Elastin network continues post-birth, remodeled into more tightly organized elastin bundles located around alveolar openings.

Specimen 6E: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: alveolar system Present Regionally restricted 6E Elastin network continues post-birth, remodeled into more tightly organized elastin bundles located around alveolar openings.

Specimen 6F: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: alveolar system Present Regionally restricted 6F Elastin network is significantly remodeled with fewer thinner fibers and more tightly organized elastin bundles around alveolar openings.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory