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Gene Expression Data
Assay Details
Assay
Reference: J:273779 Lindstrom NO, et al., Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. J Am Soc Nephrol. 2018 Mar;29(3):785-805
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6505840
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Antibody: anti-Six2 (MBS610128)
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: The authors used two Six2 antibodies; it is possible that MGI:6505815 was used to obtain some or all of these data.
Results
Specimen 4D: embryonic day 15.5 (more )
Note: Triple labeled: red - Six2; green - Krt8 (assay MGI:6505838); blue - phospho-histone 3.
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 4D Expression is seen in nephron progenitor cells beneath the kidney capsule.
Specimen 4E: postnatal day 2 (more )
Note: Triple labeled: red - Six2; green - Krt8 (assay MGI:6505838); blue - phospho-histone 3.
Structure Level Pattern Image Note
TS27: cap mesenchyme Present Regionally restricted 4E Expression is seen in nephron progenitor cells beneath the kidney capsule.
Specimen S2C: embryonic day 15.5 (more )
Note: Triple labeled: red - Six2; green - Meis1 (assay MGI:6505839); blue - Krt8 (assay MGI:6505838)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted S2C Expression is seen in nephron progenitor cells beneath the kidney capsule.
Specimen S3B - left: embryonic day 15.5 (more )
Note: Double labeled: red - Six2; gray - Krt8 (assay MGI:6505838)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted S3B left Expression is seen in nephron progenitor cells beneath the kidney capsule.
Specimen S3B - right: postnatal day 2 (more )
Note: Double labeled: red - Six2; gray - Krt8 (assay MGI:6505838)
Structure Level Pattern Image Note
TS27: cap mesenchyme Present Regionally restricted S3B right Expression is seen in nephron progenitor cells beneath the kidney capsule.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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