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Gene Expression Data
Assay Details
Assay
Reference: J:298296 Zha C, et al., Biallelic variants in the small optic lobe calpain CAPN15 are associated with congenital eye anomalies, deafness and other neurodevelopmental deficits. Hum Mol Genet. 2020 Nov 4;29(18):3054-3063
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6505324
Gene symbol: Capn15
Gene name: calpain 15
Reporter: lacZ
Direct Detection
Results
Specimen 5A: embryonic day 12.0; Capn15tm2d(EUCOMM)Hmgu/Capn15+ (more )
Note: sagittal section
Structure Level Pattern Image Note
TS20: hindbrain mantle layer Present 5A Expression is seen in the mantle zones of the pallium, subpallium and rhombomere.
TS20: telencephalon mantle layer Present 5A Expression is seen in the mantle zones of the pallium, subpallium and rhombomere.
Specimen 5B: embryonic day 18.0; Capn15tm2d(EUCOMM)Hmgu/Capn15+ (more )
Note: coronal section
Structure Level Pattern Image Note
TS26: brain Present Widespread 5B
TS26: brain subventricular zone Strong 5B
TS26: cerebral cortex Present Non-Uniform 5B Expression is strongest in the deep cortical layer.
TS26: hippocampus Present Non-Uniform 5B Expression is seen in the neuroepithelium but not the pyramidal layer.
Specimen 5C: postnatal day 3; Capn15tm2d(EUCOMM)Hmgu/Capn15+ (more )
Note: coronal section
Structure Level Pattern Image Note
TS27: hippocampus Present 5C
Specimen not shown: postnatal day 3; Capn15tm2d(EUCOMM)Hmgu/Capn15+ (more )
Structure Level Pattern Image Note
TS27: brain Present Ubiquitous
TS27: cerebellum Present
TS27: main olfactory bulb Present
Specimen 5D: postnatal day 3; Capn15tm2d(EUCOMM)Hmgu/Capn15+ (more )
Note: sagittal section
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Present 5D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory