Tg(MX1,MX2*)#Stae
Transgene Detail
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| Symbol: |
Tg(MX1,MX2*)#Stae |
| Name: |
transgene insertion, Peter Staeheli |
| MGI ID: |
MGI:6504268 |
| Synonyms: |
hMx-tg, MxAtg |
| Transgene: |
Tg(MX1,MX2*)#Stae Location: unknown
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| Alliance: |
Tg(MX1,MX2*)#Stae page
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| Strain of Origin: |
C57BL/6 x SJL
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(MX1,MX2*)#Stae expresses
2 genes
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
MX1 (4599) |
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MX2 null allele owing to an unintentional deletion that includes exon 4 |
| human |
MX2 (4600) |
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Mutation details: The transgene consists of human BAC RP11-120C17, containing the 3' end of the FAM3B gene, the complete MX2 and MX1 genes, and the 3' end of the TMPRSS2 gene. The MX2 gene is a null allele in these transgenic mice owing to an unintentional deletion that includes exon 4.
(J:242012)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:242012 Deeg CM, et al., In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein. J Exp Med. 2017 May 01;214(5):1239-1248 |
| All: |
2 reference(s) |
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Analysis Tools
