Gp1batm1.1(icre)Yose
Targeted Allele Detail
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Symbol: |
Gp1batm1.1(icre)Yose |
Name: |
glycoprotein 1b, alpha polypeptide; targeted mutation 1.1, Yotis A Senis |
MGI ID: |
MGI:6504221 |
Synonyms: |
Gp1ba-Cre |
Gene: |
Gp1ba Location: Chr11:70529948-70532862 bp, + strand Genetic Position: Chr11, 43.2 cM
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Alliance: |
Gp1batm1.1(icre)Yose page
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Germline Transmission: |
Earliest citation of germline transmission:
J:273209
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Gp1batm1.1(icre)Yose expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The targeting vector inserted a T2A sequence, improved cre recombinase gene inserted between the last amino acid of of the coding sequence and the termination sequence. Flp-mediated recombination removed an FRT-flanked puromycin resistance cassette inserted downstream of the stop codon.
(J:273209)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Gp1ba
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gp1ba Mutation: |
27 strains or lines available
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Original: |
J:273209 Nagy Z, et al., The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions. Blood. 2019 Jan 24;133(4):331-343 |
All: |
1 reference(s) |
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