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Gene Expression Data
Assay Details
Assay
Reference: J:33995 Gulisano M, et al., Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex in the mouse. Eur J Neurosci. 1996 May;8(5):1037-50
Assay type: RNA in situ
MGI Accession ID: MGI:6503887
Gene symbol: Emx2
Gene name: empty spiracles homeobox 2
Probe: Emx2 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present Widespread 1A Authors report that, at E12.5, practically entire cortex coincides with ventricular zone; expression is throughout.
TS20: cerebral cortex intermediate zone Absent 1A Expression excluded from transitional field (subventricular zone and intermediate zone) and from the cortical plate.
TS20: cerebral cortex subventricular zone Absent 1A Expression excluded from transitional field (subventricular zone and intermediate zone) and from the cortical plate.
TS20: cortical plate Absent 1A Expression excluded from transitional field (subventricular zone and intermediate zone) and from the cortical plate.
TS20: ganglionic eminence Trace 1A Faint expression in non-cortical regions of telencephalon - e.g. ganglionic eminence.

Specimen 1B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present Graded 1B Expression confined to germinal ventricular zone representing only part of developing cortex. Anterior-to-posterior gradient of expression.
TS22: cerebral cortex intermediate zone Absent 1B Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS22: cerebral cortex subventricular zone Absent 1B Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS22: cortical plate Absent 1B Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS22: ganglionic eminence Trace 1B Faint expression in non-cortical regions of telencephalon - e.g. ganglionic eminence.

Specimen 1C: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 1C Expression in germinal ventricular zone.
TS24: cerebral cortex intermediate zone Absent 1C Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS24: cerebral cortex subventricular zone Absent 1C Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS24: cortical plate Absent 1C Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.

Specimen 1D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Present 1D Expression in germinal ventricular zone.
TS26: cerebral cortex intermediate zone Absent 1D Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS26: cerebral cortex subventricular zone Absent 1D Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS26: cortical plate Absent 1D Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.

Specimen 1E: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex ventricular zone Present 1E Expression in germinal ventricular zone.
TS27: cerebral cortex intermediate zone Absent 1E Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS27: cerebral cortex subventricular zone Absent 1E Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS27: cortical plate Absent 1E Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS27: main olfactory bulb mitral cell layer Present 1E

Specimen 2B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 2B Expression in ventricular zone. Expression correlates with position of proliferative epithelium.
TS20: cerebral cortex intermediate zone Absent 2B Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate. Expression is absent in intermediate zone in ventrolateral cortical regions.
TS20: cerebral cortex subventricular zone Absent 2B Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate. Expression is absent in intermediate zone in ventrolateral cortical regions.
TS20: cortical plate Absent 2B Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate. Expression is absent in intermediate zone in ventrolateral cortical regions.
TS20: cerebral cortex Present Regionally restricted 2B No expression in migrating postmitotic neurons.
TS20: ganglionic eminence Trace 2B Faint expression in non-cortical regions of telencephalon - e.g. ganglionic eminence.

Specimen 2E: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 2E Expression in ventricular zone. Expression correlates with position of proliferative epithelium.
TS22: cerebral cortex intermediate zone Absent 2E Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS22: cerebral cortex subventricular zone Absent 2E Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS22: cortical plate Absent 2E Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS22: telencephalon pia mater Present 2E

Specimen 2H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 2H Expression in ventricular zone. Expression correlates with position of proliferative epithelium.
TS24: cerebral cortex intermediate zone Absent 2H Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS24: cerebral cortex subventricular zone Absent 2H Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS24: cortical plate Absent 2H Expression excluded from transitional field, comprising subventricular zone and intermediate zone, and from the cortical plate.
TS24: telencephalon pia mater Present 2H


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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory