Tg(CAG-GFP,-Prss2*)#Bji
Transgene Detail
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| Symbol: |
Tg(CAG-GFP,-Prss2*)#Bji |
| Name: |
transgene insertion, Baoan Ji |
| MGI ID: |
MGI:6501771 |
| Synonyms: |
LGL-PACE trypsinogen |
| Transgene: |
Tg(CAG-GFP,-Prss2*)#Bji Location: unknown
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| Alliance: |
Tg(CAG-GFP,-Prss2*)#Bji page
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| Strain of Origin: |
Not Applicable
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| Transgene Type: |
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Transgenic (Conditional ready, Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Mutation details: The CAG promoter drives expresison of a floxed GFP and STOP cassette, and the paired basic amino acid-cleaving enzyme (PACE) rat Prss2 gene with a 5' signal peptide, trypsinogen activation peptide, and hemagglutinin tag. The original enteropeptidase cleavage site (DDDDK) was replaced by a PACE cleavage site (RTKR).
(J:194451)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:194451 Gaiser S, et al., Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis. Gut. 2011 Oct;60(10):1379-88 |
| All: |
2 reference(s) |
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Analysis Tools
