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Gene Expression Data
Assay Details
Assay
Reference: J:159519 Saharinen P, et al., Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev. 2010 May;24(9):875-80
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6501776
Gene symbol: Flt4
Gene name: FMS-like tyrosine kinase 4
Reporter: lacZ
Direct Detection
Results
Specimen S8G (left): postnatal adult; Flt4tm1Ali/Flt4+, Tmem204tm1.1Ali/Tmem204tm1.1Ali (more )
Structure Level Pattern Image Note
TS28: heart Present Regionally restricted S8G (left) Authors report enlarged lymphatic vessels in various organs.
TS28: lymphatic vessel Present Regionally restricted S8G (left) Authors report enlarged lymphatic vessels in various organs.
Specimen S8G (right): postnatal adult; Flt4tm1Ali/Flt4+, Tmem204tm1.1Ali/Tmem204+ (more )
Structure Level Pattern Image Note
TS28: heart Present Regionally restricted S8G (right)
TS28: lymphatic vessel Present Regionally restricted S8G (right)
Specimen S8H (left): postnatal adult; Flt4tm1Ali/Flt4+, Tmem204tm1.1Ali/Tmem204tm1.1Ali (more )
Structure Level Pattern Image Note
TS28: lung Present Regionally restricted S8H (left) Authors report enlarged lymphatic vessels in various organs.
TS28: lymphatic vessel Present Regionally restricted S8H (left) Authors report enlarged lymphatic vessels in various organs.
Specimen S8H (right): postnatal adult; Flt4tm1Ali/Flt4+, Tmem204tm1.1Ali/Tmem204+ (more )
Structure Level Pattern Image Note
TS28: lung Present Regionally restricted S8H (right)
TS28: lymphatic vessel Present Regionally restricted S8H (right)
Specimen S8I (left): postnatal adult; Flt4tm1Ali/Flt4+, Tmem204tm1.1Ali/Tmem204tm1.1Ali (more )
Structure Level Pattern Image Note
TS28: intestine Present Regionally restricted S8I (left) Authors report enlarged lymphatic vessels in various organs.
TS28: lymphatic vessel Present Regionally restricted S8I (left) Authors report enlarged lymphatic vessels in various organs.
Specimen S8I (right): postnatal adult; Flt4tm1Ali/Flt4+, Tmem204tm1.1Ali/Tmem204+ (more )
Structure Level Pattern Image Note
TS28: intestine Present Regionally restricted S8I (right)
TS28: lymphatic vessel Present Regionally restricted S8I (right)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory