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Gene Expression Data
Assay Details
Assay
Reference: J:295931 Barque A, et al., Knockout of the gene encoding the extracellular matrix protein SNED1 results in early neonatal lethality and craniofacial malformations. Dev Dyn. 2020 Oct 4;
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6491225
Gene symbol: Sned1
Gene name: sushi, nidogen and EGF-like domains 1
Reporter: lacZ
Direct Detection
Results
Specimen 6A: embryonic day 11.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Present 6A
TS19: branchial arch Present 6A
TS19: lung Present 6A
TS19: nasal process Present 6A
TS19: somite Present 6A
Specimen 6B: embryonic day 11.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS19: branchial arch Present 6B
TS19: nasal process Present 6B
Specimen 6C left: embryonic day 11.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS19: somite Present Regionally restricted 6C left Expression is in the ventromedial cells of the somites.
TS19: Rathke's pouch Present 6C left
TS19: lung Present 6C left
Specimen 6C right: embryonic day 11.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS19: somite Present Regionally restricted 6C right Expression is in the ventromedial cells of the somites.
TS19: Rathke's pouch Present 6C right
TS19: lung Present 6C right
Specimen 6D: embryonic day 13.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS21: head Present Regionally restricted 6D Expression is in the derivatives of the pharyngeal arches.
TS21: Meckel's cartilage Present 6D
TS21: choroid plexus Present 6D
TS21: humerus cartilage condensation Present 6D
TS21: limb Present 6D
TS21: rib pre-cartilage condensation Present 6D
TS21: scapula pre-cartilage condensation Present 6D
TS21: somite Present 6D
TS21: tongue Present 6D
TS21: trunk mesenchyme Present 6D
TS21: vertebral pre-cartilage condensation Present 6D
TS21: vomeronasal organ Present 6D
TS21: nasal septum mesenchyme Present Regionally restricted 6D Expression is in the cartilage primordium of the nasal septum.
Specimen 6E: embryonic day 13.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS21: Meckel's cartilage Present 6E
TS21: humerus cartilage condensation Present 6E
TS21: scapula pre-cartilage condensation Present 6E
TS21: tongue Present 6E
TS21: vomeronasal organ Present 6E
TS21: nasal septum mesenchyme Present Regionally restricted 6E Expression is in the cartilage primordium of the nasal septum.
Specimen 6F: embryonic day 13.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS21: limb Present 6F
Specimen 6G left: embryonic day 13.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS21: Meckel's cartilage Present 6G left
TS21: choroid plexus Present 6G left
TS21: limb Present 6G left
TS21: rib pre-cartilage condensation Present 6G left
TS21: tongue Present 6G left
TS21: trunk mesenchyme Present Regionally restricted 6G left Expression is in the mesenchyme surrounding the dorsal root ganglia.
TS21: somite Strong Regionally restricted 6G left Expression is along the antero-posterior axis, with the posterior somites the most intensely stained.
Specimen 6G middle: embryonic day 13.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS21: Meckel's cartilage Present 6G middle
TS21: choroid plexus Present 6G middle
TS21: tongue Present 6G middle
TS21: trunk mesenchyme Present Regionally restricted 6G middle Expression is in the mesenchyme surrounding the dorsal root ganglia.
TS21: somite Strong Regionally restricted 6G middle xpression is along the antero-posterior axis, with the posterior somites the most intensely stained.
Specimen 6G right: embryonic day 13.5; Sned1tm1a(KOMP)Wtsi/Sned1+ (more )
Structure Level Pattern Image Note
TS21: somite Strong Regionally restricted 6G right Expression is along the antero-posterior axis, with the posterior somites the most intensely stained.
TS21: choroid plexus Present 6G right
TS21: vertebral pre-cartilage condensation Present 6G right
TS21: nasal septum mesenchyme Present Regionally restricted 6G right Expression is in the cartilage primordium of the nasal septum.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory