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Gene Expression Data
Assay Details
Assay
Reference: J:193583 Cai Y, et al., Nuclear receptor COUP-TFII-expressing neocortical interneurons are derived from the medial and lateral/caudal ganglionic eminence and define specific subsets of mature interneurons. J Comp Neurol. 2013 Feb 1;521(2):479-97
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6490538
Gene symbol: Sp8
Gene name: trans-acting transcription factor 8
Antibody: Sp8 (C-18): sc-104661
Detection system: Secondary antibody
Results
Specimen 2A/C: embryonic day 16.5 (more )
Note: Triple labeled: green - Sp8; magenta - Nr2f2 (assay MGI:6490533); blue - Nkx2-1 (assay MGI:6490532).
Structure Level Pattern Image Note
TS24: lateral ganglionic eminence Present 2A , 2C
TS24: neocortex Present Regionally restricted 2A , 2C There was a migratory stream from the dorsal lateral ganglionic eminence to the neocortex through the subventricular zone. The majority of cells in the stream were Nr2f2+Sp8+.
TS24: cerebral cortex subventricular zone Present 2C , 2A
Specimen 2E/G: embryonic day 16.5 (more )
Note: Triple labeled: green - Sp8; magenta - Nr2f2 (assay MGI:6490533); blue - Nkx2-1 (assay MGI:6490532).
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 2E , 2G There was a migratory stream from the dorsal lateral ganglionic eminence to the neocortex through the subventricular zone. The majority of cells in the stream were Nr2f2+Sp8+.
TS24: cerebral cortex subventricular zone Present 2E , 2G
TS24: lateral ganglionic eminence Present 2E , 2G
Specimen 2I/K: embryonic day 16.5 (more )
Note: Triple labeled: green - Sp8; magenta - Nr2f2 (assay MGI:6490533); blue - Nkx2-1 (assay MGI:6490532).
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 2I , 2K There was a migratory stream from the dorsal caudal ganglionic eminence to the neocortex through the subventricular zone. The majority of cells in the stream were Nr2f2+Sp8+.
TS24: caudal ganglionic eminence Present 2I , 2K
TS24: cerebral cortex subventricular zone Present 2I , 2K
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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