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Gene Expression Data
Assay Details
Assay
Reference: J:173507 Du X, et al., Differential expression pattern of ZAC in developing mouse and human pancreas. J Mol Histol. 2011 Apr;42(2):129-36
Assay type: RNA in situ
MGI Accession ID: MGI:6490460
Gene symbol: Plagl1
Gene name: pleiomorphic adenoma gene-like 1
Probe: Zac1 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: rib cartilage condensation Strong 2A Highly expressed in chondrogenic sites.
Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain Strong 2B Highly expressed in nervous system.
Specimen 2C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tongue muscle Strong 2C Highly expressed in skeletal muscle.
Specimen 2D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pancreas primordium dorsal bud Present 2D Expression in dorsal pancreas.
TS19: pancreas primordium mesenchyme Present Regionally restricted 2D Expression in mesenchyme surrounding and within pancreas.
Specimen 2E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pancreas mesenchyme Present Regionally restricted 2E Expression in mesenchyme surrounding and within pancreas.
Specimen 2F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pancreas mesenchyme Weak 2F Expression in mesenchyme decreased by E15.5.
Specimen 2G: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: pancreas Ambiguous 2G
Specimen 3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pancreas primordium mesenchyme Present Regionally restricted 3A Expression in mesenchyme surrounding and within pancreas.
TS19: pancreas primordium epithelium Weak 3A Very weak expression in epithelium at E11.5.
Specimen 3B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pancreas primordium mesenchyme Present Regionally restricted 3B Expression in mesenchyme surrounding and within pancreas.
TS19: pancreas primordium epithelium Present 3B Very weak expression in epithelium at E11.5.
Specimen 3D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pancreas mesenchyme Present Regionally restricted 3D Expression in mesenchyme surrounding and within pancreas.
Specimen 3E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pancreas mesenchyme Present Regionally restricted 3E Expression in mesenchyme surrounding and within pancreas.
TS21: pancreatic acinus Present Regionally restricted 3E Expression in acinar cells at tips of branching epithelium.
Specimen 3G/I: embryonic day 13.5 (more )
Note: Double labeled: blue - Plagl1; red - Ins1 (assay MGI:6490458) and Ins2 (assay MGI:6490459).
Structure Level Pattern Image Note
TS21: pancreas epithelium Present Regionally restricted 3I , 3G No expression in insulin-expressing cells.
Specimen 3K/M: embryonic day 15.5 (more )
Note: Double labeled: blue - Plagl1; red - Ins1 (assay MGI:6490458) and Ins2 (assay MGI:6490459).
Structure Level Pattern Image Note
TS23: pancreatic acinus Weak 3M , 3K Low level of expression in acinar cells.
TS23: endocrine pancreas Absent 3K , 3M No expression in insulin-expressing cells.
Specimen 3O/Q: embryonic day 17.5 (more )
Note: Double labeled: blue - Plagl1; red - Ins1 (assay MGI:6490458) and Ins2 (assay MGI:6490459).
Structure Level Pattern Image Note
TS25: pancreatic acinus Weak 3O , 3Q Low level of expression in acinar cells.
TS25: endocrine pancreas Absent 3Q , 3O No expression in insulin-expressing cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory