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Gene Expression Data
Assay Details
Assay
Reference: J:112231 Wang SZ, et al., An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development. 2006 Sep;133(17):3389-98
Assay type: RNA in situ
MGI Accession ID: MGI:6489936
Gene symbol: Zfp488
Gene name: zinc finger protein 488
Probe: Zfp488 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Absent 2A No expression in ventral spinal cord.

Specimen 2D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Present Regionally restricted 2D Expression initially detected at E14.5 as foci in ventral ventricular domain.
TS22: dorsal root ganglion Absent 2D Expression initially detected at E14.5 as foci in ventral ventricular domain.

Specimen 2G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: spinal cord white matter Present Regionally restricted 2G Expression extends to ventral white matter of spinal cord.

Specimen 3A: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: spinal cord white matter Present 3A Expression mainly confined to spinal white matter.
TS28: spinal cord gray matter Present Regionally restricted 3A Expression in small population of cells in gray matter of spinal cord.

Specimen 3B: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral hemisphere white matter Strong Regionally restricted 3B Expression highly enriched in white matter of cerebral cortex.
TS28: cerebral hemisphere gray matter Present Regionally restricted 3B Expression in small population of cells in gray matter of forebrain.

Specimen 3C: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Strong Regionally restricted 3C Expression highly enriched in white matter of cerebellum.

Specimen 3D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: optic nerve Present Regionally restricted 3D Expression highly enriched in white matter of optic nerve. Expression in cells forming a linear array, a characteristic of interfascicular myelinating oligodendrocytes.

Specimen 3E: postnatal day 14 (more )
Note: Double labeled: blue - Zfp488; brown - Plp1 (assay MGI:6489941).
Structure Level Pattern Image Note
TS28: corpus callosum Present Regionally restricted 3E Majority of expressing cells co-express Plp1. Expression in cells forming a linear array, a characteristic of interfascicular myelinating oligodendrocytes.

Specimen 3F: postnatal day 14 (more )
Note: Double labeled: blue - Zfp488; brown - Pdgfra (assay MGI:6489940).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 3F Expression largely absent in Pdgfra-expressing oligodendrocyte precursors.

Specimen 4A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: spinal cord white matter Present 4A

Specimen 4B: embryonic day 18.5; Olig1tm1(cre)Rth/Olig1tm1(cre)Rth (more )
Structure Level Pattern Image Note
TS26: spinal cord white matter Absent 4B

Specimen 4C: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present Regionally restricted 4C Expression in white matter of corpus callosum.

Specimen 4D: postnatal day 14; Olig1tm1(cre)Rth/Olig1tm1(cre)Rth (more )
Structure Level Pattern Image Note
TS28: corpus callosum Absent 4D

Specimen 4E: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Present 4E

Specimen 4F: postnatal day 14; Olig1tm1(cre)Rth/Olig1tm1(cre)Rth (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Absent 4F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory