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Gene Expression Data
Assay Details
Assay
Reference: J:90568 Relaix F, et al., Divergent functions of murine Pax3 and Pax7 in limb muscle development. Genes Dev. 2004 May 1;18(9):1088-105
Assay type: RNA in situ
MGI Accession ID: MGI:6488465
Gene symbol: Pax7
Gene name: paired box 7
Probe: Pax7 probe9
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1I: embryonic day 10.5; Pax3tm1Buck/Pax3+ (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1I Expression in dorsal neural tube.
TS17: branchial arch Present 1I
TS17: fronto-nasal process Present 1I
TS17: somite Present 1I
TS17: limb mesenchyme Absent 1I No expression in limb progenitor muscles.
Specimen 1J: embryonic day 10.5; Pax3tm1Buck/Pax3tm1Buck (more )
Structure Level Pattern Image Note
TS17: somite Weak 1J Expression reduced in somites due to cell death.
TS17: branchial arch Present 1J Expression not affected in branchial arches.
Specimen 1L: embryonic day 10.5; Pax3tm1Buck/Pax3+ (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1L Expression in dorsal neural tube, expression is absent from dorsal-most region.
TS17: somite Present Regionally restricted 1L Expression in central dermomyotome, but not in epaxial and hypoaxial-most regions.
Specimen 1M: embryonic day 10.5; Pax3tm1Buck/Pax3tm1Buck (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1M Neural tube expression appears unaffected.
TS17: somite Trace 1M Expression in somite is severely reduced due to cell death.
Specimen 1O: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Absent 1O Expression not detected in muscle progenitor cells migrating to limb.
Specimen 1P: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 1P Expression first detected at E11.5 in proximal muscle masses.
Specimen 1Q: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present Regionally restricted 1Q Expression in more distal limb muscles at E12.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory