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Gene Expression Data
Assay Details
Assay
Reference: J:282084 Ibaraki K, et al., Expression Analyses of POGZ, A Responsible Gene for Neurodevelopmental Disorders, during Mouse Brain Development. Dev Neurosci. 2019;41(1-2):139-148
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6488196
Gene symbol: Pogz
Gene name: pogo transposable element with ZNF domain
Antibody: anti-POGZ
Detection system: Secondary antibody
Results
Specimen 2Aa: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present 2Aa Expression is present in the progenitor/stem cells.
TS21: cerebral cortex Strong Single cells 2Aa Strong staining was seen in relatively large cells; they were believed to be subplate neurons, although that was not definitively proven.
TS21: cortical subplate Ambiguous Single cells 2Aa Strong staining was seen in relatively large cells; they were believed to be subplate neurons, although that was not definitively proven.

Specimen 2Ab/Ba: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cortical plate Present 2Ab , 2Ba CP-M , 2Ba CP-L , 2Ba CP-U Expression is present in neurons.
TS23: cerebral cortex subventricular zone Present 2Ab Expression is present in the progenitor/stem cells.
TS23: cerebral cortex ventricular layer Present 2Ab Expression is present in the progenitor/stem cells.
TS23: cerebral cortex intermediate zone Weak 2Ab , 2Ba IZ

Specimen 2Ac/Bb: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: cortical plate Present 2Bb CP-L , 2Bb CP-U , 2Bb CP-M , 2Ac Expression is present in neurons.
TS25: cerebral cortex subventricular zone Present 2Ac Expression is present in the progenitor/stem cells.
TS25: cerebral cortex ventricular layer Present 2Ac Expression is present in the progenitor/stem cells.
TS25: cerebral cortex intermediate zone Weak 2Ac , 2Bb IZ

Specimen 2Ad/Bc: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical plate Present 2Bc CP-U , 2Bc CP-M , 2Ad , 2Bc CP-L
TS27: cerebral cortex intermediate zone Weak 2Ad , 2Bc IZ

Specimen 2Ae/Bd: postnatal day 7 (more )
Structure Level Pattern Image Note
TS27: cortical layer I Present 2Ae Expression is detected in almost all cells of the cerebral cortex.
TS27: cortical layer II Present 2Ae , 2Bd II-III Expression is detected in almost all cells of the cerebral cortex.
TS27: cortical layer III Present 2Ae , 2Bd II-III Expression is detected in almost all cells of the cerebral cortex.
TS27: cortical layer IV Present 2Bd IV , 2Ae Expression is detected in almost all cells of the cerebral cortex.
TS27: cortical layer V Present 2Bd V , 2Ae Expression is detected in almost all cells of the cerebral cortex.
TS27: cortical layer VI Present 2Ae , 2Bd VI Expression is detected in almost all cells of the cerebral cortex.

Specimen 2Af/Be: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: cortical layer I Weak 2Af Expression is detected in almost all cells of the cerebral cortex.
TS28: cortical layer II Weak 2Af , 2Be II-III Expression is detected in almost all cells of the cerebral cortex.
TS28: cortical layer III Weak 2Af , 2Be II-III Expression is detected in almost all cells of the cerebral cortex.
TS28: cortical layer IV Weak 2Af , 2Be IV Expression is detected in almost all cells of the cerebral cortex.
TS28: cortical layer V Weak 2Be V , 2Af Expression is detected in almost all cells of the cerebral cortex.
TS28: cortical layer VI Weak 2Be VI , 2Af Expression is detected in almost all cells of the cerebral cortex.

Specimen 2Ca: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present 2Ca Expression is seen in neurons.

Specimen 3A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: hippocampus Strong Non-Uniform 3Ac , 3Aa , 3Ab Expression is strong for pyramidal neurons in the future CA1 region; there is little expression in the migrating neurons in the intermediate zone.

Specimen 3B: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: hippocampus Strong Non-Uniform 3Bb , 3Ba , 3Bc Expression is strong for pyramidal neurons in the future CA1 region; there is little expression in the migrating neurons in the intermediate zone.
TS25: dentate gyrus Present 3Bd , 3Ba Expression is detected in granule cells at the time of dentate gyrus formation

Specimen 3C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA1 Present 3Cb , 3Ca
TS27: dentate gyrus Present 3Ca , 3Cc

Specimen 3D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present 3Da , 3Db
TS28: dentate gyrus Present 3Dc , 3Da

Specimen 3E: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Weak 3Ea , 3Eb
TS28: dentate gyrus Weak 3Ec , 3Ea

Specimen 3Fa: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: hippocampus Present 3Fa Expression is seen in cells of the CA region.

Specimen 4A: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 4Ab , 4Ac , 4Aa Expression is seen in the nucleus of Purkinje cells.
TS28: cerebellum internal granule cell layer Present Single cells 4Aa , 4Ac , 4Ab Expression is seen in a limited number of cells.
TS28: cerebellum external granule cell layer Absent 4Aa , 4Ab , 4Ac

Specimen 4B: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 4Bb , 4Bc , 4Ba
TS28: cerebellum molecular layer Present 4Bb , 4Bc , 4Ba
TS28: cerebellum granule cell layer Present 4Bb , 4Ba , 4Bc

Specimen 4C: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Absent 4Ca , 4Cc , 4Cb
TS28: cerebellum molecular layer Present 4Cb , 4Cc , 4Ca
TS28: cerebellum granule cell layer Present 4Cc , 4Ca , 4Cb

Specimen 4Da: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 4Da


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory