Arx Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:88461 Poirier K, et al., Neuroanatomical distribution of ARX in brain and its localisation in GABAergic neurons. Brain Res Mol Brain Res. 2004 Mar 17;122(1):35-46
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6479814
Gene symbol:	Arx
Gene name:	aristaless related homeobox

Antibody:	anti-ARX-HD
Detection system:	Secondary antibody coupled to fluorescein

Results

Specimen 2Ab: embryonic day 13.5 (more

)
Note: Double labeled: green - Arx; red - Tubb3 (assay MGI:6479824).

Structure	Level	Pattern	Image	Note
TS21: cerebral cortex ventricular layer	Strong		2Ac , 2Ab
TS21: corpus striatum	Strong		2Ac , 2Ab
TS21: ganglionic eminence	Strong	Regionally restricted	2Ab , 2Ac	Expression is in the intermediate zone.
TS21: cortical preplate	Strong	Regionally restricted	2Ab , 2Ac	Expression in the pre-plate layer adjacent to the medial ganglionic eminence is higher than in the preplate corresponding to a more anterior region of the developing telencephalon.

Specimen 2Bh: embryonic day 16.5 (more

)
Note: Double labeled: green - Arx; red - Reln (assay MGI:6479822).

Structure	Level	Pattern	Image	Note
TS24: cerebral cortex marginal layer	Present		2Bi , 2Bh
TS24: cerebral cortex ventricular layer	Present		2Bi , 2Bh
TS24: cerebral cortex intermediate zone	Present	Regionally restricted	2Bi , 2Bh	Expression is in migrating neurons.
TS24: cortical plate	Present	Regionally restricted	2Bi , 2Bh	Expression is in migrating neurons.

Specimen 2Bl: embryonic day 16.5 (more

)
Note: Double labeled: green - Arx; red - Reln (assay MGI:6479822).

Structure	Level	Pattern	Image	Note
TS24: cerebral cortex marginal layer	Present		2Bl , 2Bm
TS24: cerebral cortex ventricular layer	Present		2Bl , 2Bm
TS24: cerebral cortex intermediate zone	Present	Regionally restricted	2Bm , 2Bl	Expression is in migrating neurons.
TS24: cortical plate	Present	Regionally restricted	2Bm , 2Bl	Expression is in migrating neurons.

Specimen 2Bp: embryonic day 16.5 (more

)
Note: Double labeled: green - Arx; red - Reln (assay MGI:6479822).

Structure	Level	Pattern	Image	Note
TS24: cerebral cortex marginal layer	Present		2Bq , 2Bp
TS24: cerebral cortex ventricular layer	Present		2Bq , 2Bp
TS24: cerebral cortex intermediate zone	Present	Regionally restricted	2Bq , 2Bp	Expression is in migrating neurons.
TS24: cortical plate	Present	Regionally restricted	2Bq , 2Bp	Expression is in migrating neurons.

Specimen 4a: postnatal adult (more

)

Structure	Level	Pattern	Image
TS28: cortical layer I	Present	Single cells	4Aa , 4Ak
TS28: cortical layer II	Present	Single cells	4Aa , 4Ak
TS28: cortical layer III	Present	Single cells	4Aa , 4Ak
TS28: cortical layer IV	Present	Single cells	4Aa , 4Ak
TS28: cortical layer V	Present	Single cells	4Aa , 4Ak
TS28: cortical layer VI	Present	Single cells	4Aa , 4Ak

Specimen 4b: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: dentate gyrus	Present		4Al , 4Ab
TS28: dentate gyrus granule cell layer	Present		4Al , 4Ab

Specimen 4c: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: hypothalamus	Present	Regionally restricted	4Ac , 4Am	Expression is in the ventral hypothalamus.

Specimen 4d: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		4Ad , 4An

Specimen 4e: postnatal adult (more

)

Structure	Level	Image
TS28: main olfactory bulb glomerular layer	Present	4Bo , 4Be
TS28: main olfactory bulb granule cell layer	Present	4Bo , 4Be
TS28: main olfactory bulb mitral cell layer	Present	4Bo , 4Be

Specimen not shown E10: embryonic day 10.0 (more

)

Structure	Level	Pattern	Note
TS16: future brain floor plate	Present	Regionally restricted
TS16: telencephalic vesicle	Present	Regionally restricted
TS16: diencephalon	Present	Regionally restricted	Expression is in the ventral thalamus.

Specimen not shown E10.5: embryonic day 10.5 (more

)

Structure	Level	Pattern	Note
TS17: telencephalon	Present	Regionally restricted	Expression is in the ganglionic eminences, the developing neocortex and the striatum.
TS17: diencephalon	Present	Regionally restricted	Expression is in the ventral thalamus.
TS17: neural tube	Present

Specimen not shown Adult: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: amygdala	Present
TS28: cerebellum	Absent

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24