Gene Expression Data
Assay Details
Assay
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Reference:
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J:62599
Vialard F, et al., Overexpression of mSim2 gene in the zona limitans of the diencephalon of segmental trisomy 16 Ts1Cje fetuses, a mouse model for trisomy 21: a novel whole-mount based RNA hybridization study. Brain Res Dev Brain Res. 2000 May 11;121(1):73-8
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6479680
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Gene symbol:
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Sim1
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Gene name:
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single-minded family bHLH transcription factor 1
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Probe:
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Sim1 cDNA7
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
3a1:
embryonic day 12.5; Ts(16C-tel)1Cje/0
(more )
Note: Hemisected fetus.
Specimen
3a1:
(close )
Genetic Background:
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involves: C57BL/6 * C57BL/6J * Rb(11.16)2H/H * Rb(16.17)32Lub
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Mutant Allele(s):
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Ts(16C-tel)1Cje/0
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Hemisected fetus.
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Structure |
Level |
Pattern |
Image |
Note |
TS20: zona limitans intrathalamica |
Present |
Regionally restricted |
3a1
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Expression is at the base and there were no significant differences in expression between control and Ts1Cje trisomic mice.
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Specimen
3a2:
embryonic day 12.5
(more )
Note: Hemisected fetus.
Specimen
3a2:
(close )
Genetic Background:
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involves: C57BL/6 * C57BL/6J
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Hemisected fetus.
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