Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Ar*C556G,-EGFP)NCWhw
Name:	transgene insertion NC, William H Walker
MGI ID:	MGI:6478903
Synonyms:	AR-NC
Transgene:	Tg(Ar*C556G,-EGFP)NCWhw  Location: unknown
Alliance:	Tg(Ar*C556G,-EGFP)NCWhw page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Mutation details: This transgene includes a 167 kb genomic mouse Ar gene and approximately 40 kb each of 5' and 3' flanking sequence. An IRES, EGFP reporter gene, and poly A site are present after the stop codon for Ar to coexpress AR and EGFP. There is a one base pair mutation in exon 2 resulting in a C556G amino acid change in the mouse AR protein. (J:310653)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:310653 Cooke PS, et al., Male fertility in mice requires classical and nonclassical androgen signaling. Cell Rep. 2021 Aug 17;36(7):109557
All:	2 reference(s)