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Tg(Ar*,-EGFP)CWhw
Transgene Detail
Summary
Symbol: Tg(Ar*,-EGFP)CWhw
Name: transgene insertion C, William H Walker
MGI ID: MGI:6478902
Synonyms: AR-C
Transgene: Tg(Ar*,-EGFP)CWhw  Location: unknown  
Alliance: Tg(Ar*,-EGFP)CWhw page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene includes a 167 kb genomic mouse Ar gene and approximately 40 kb each of 5' and 3' flanking sequence. An IRES, EGFP reoporter gene, and poly A site are present after the stop codon for Ar to co-express AR and EGFP. There is a deletion of 45 base pairs in exon 1 of the mouse androgen receptor gene resulting in the deletion of 15 amino acids (363-377). (J:310653)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:310653 Cooke PS, et al., Male fertility in mice requires classical and nonclassical androgen signaling. Cell Rep. 2021 Aug 17;36(7):109557
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory