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Gene Expression Data
Assay Details
Assay
Reference: J:231660 Punzo D, et al., Age-Related Changes in d-Aspartate Oxidase Promoter Methylation Control Extracellular d-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging. J Neurosci. 2016 Mar 9;36(10):3064-78
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6478322
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Detection system: Secondary antibody coupled to Oregon Green 488
Assay notes: Vibratome sections.
Results
Specimen 7a 0.5 months +/+: postnatal month 0.5 (more )
Note: Double labeled with lipofuscin (red).
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 7a 0.5 months Ddo+/+ Expression is in dopaminergic neurons.
Specimen 7a 0.5 months -/-: postnatal month 0.5; Ddotm1Rdl/Ddotm1Rdl (more )
Note: Double labeled with lipofuscin (red).
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 7a 0.5 months Ddo-/- Expression is in dopaminergic neurons.
Specimen 7a 3 months +/+: postnatal month 3 (more )
Note: Double labeled with lipofuscin (red).
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 7a 3 months Ddo+/+ Expression is in dopaminergic neurons.
Specimen 7a 3 months -/-: postnatal month 3; Ddotm1Rdl/Ddotm1Rdl (more )
Note: Double labeled with lipofuscin (red).
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 7a 3 months Ddo-/- Expression is in dopaminergic neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory