Aif1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:231660 Punzo D, et al., Age-Related Changes in d-Aspartate Oxidase Promoter Methylation Control Extracellular d-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging. J Neurosci. 2016 Mar 9;36(10):3064-78
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6478316
Gene symbol:	Aif1
Gene name:	allograft inflammatory factor 1

Antibody:	anti-Iba-1
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

5g Ddo+/+ 10 months ©

Specimen 5g 10 months +/+: postnatal month 10 (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Ddo+/+ 10 months

5g Ddo-/- 10 months ©

Specimen 5g 10 months -/-: postnatal month 10; Ddo^tm1Rdl/Ddo^tm1Rdl (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Ddo-/- 10 months

5g Ddo+/+ 13 months ©

Specimen 5g 13 months +/+: postnatal month 13 (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Ddo+/+ 13 months

5g Ddo-/- 13 months ©

Specimen 5g 13 months -/-: postnatal month 13; Ddo^tm1Rdl/Ddo^tm1Rdl (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Ddo-/- 13 months

5g Ddo+/+ 10 months right ©

Specimen 5g 10 months +/+ right: postnatal month 10 (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Ddo+/+ 10 months right

5g Ddo-/- 10 months right ©

Specimen 5g 10 months -/- right: postnatal month 10; Ddo^tm1Rdl/Ddo^tm1Rdl (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Ddo-/- 10 months right

5g Ddo+/+ 13 months right ©

Specimen 5g 13 months +/+ right: postnatal month 13 (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Ddo+/+ 13 months right

5g Ddo-/- 13 months right ©

Specimen 5g 13 months -/- right: postnatal month 13; Ddo^tm1Rdl/Ddo^tm1Rdl (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Ddo-/- 13 months right

5g Resting ©

Specimen 5g Resting: postnatal month 13; Ddo^tm1Rdl/Ddo^tm1Rdl (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Resting

5g Reactive ©

Specimen 5g Reactive: postnatal month 13; Ddo^tm1Rdl/Ddo^tm1Rdl (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Reactive

Specimen 5g Dystrophic: postnatal month 13; Ddo^tm1Rdl/Ddo^tm1Rdl (more

)

Structure	Level	Pattern	Image	Note
TS28: substantia nigra	Present		5g Dystrophic	The number of positive dystrophic microglia has increased in this mutant compared to age-matched controls.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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