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Gene Expression Data
Assay Details
Assay
Reference: J:48402 Ohyama K, et al., Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice. Brain Res Dev Brain Res. 1998 May 15;107(2):219-26
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6478234
Gene symbol: Ptprz1
Gene name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Antibody: MAb 6B4
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixation was with 95% ethanol: 5% acetic acid.
Results
Specimen 3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 3A Expression in cell bodies of migratory dopaminergic (DA) neurons in the ventral mesencephalon during E11-E13.

Specimen 3C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: midbrain Present Regionally restricted 3C Expression in cell bodies of migratory dopaminergic (DA) neurons in the ventral mesencephalon during E11-E13.

Specimen 3E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: midbrain Present Regionally restricted 3E Expression not clearly localized in the ventral mesencephalon.

Specimen 4A: embryonic day 12.5 (more )
Note: Double labeled: dark blue - 6B4 PG (Ptprz1); brown - L1cam (assay MGI:6478231).
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted 4A Expression in laterally migrating dopaminergic (DA) neurons.

Specimen 4B: embryonic day 12.5 (more )
Note: Double labeled: dark blue - 6B4 PG (Ptprz1); brown - L1cam (assay MGI:6478231).
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted 4B Expression in DA neurons immediately before they attach to tangentially arranged fibers.

Specimen 4C: embryonic day 12.5 (more )
Note: Double labeled: dark blue - 6B4 PG (Ptprz1); brown - L1cam (assay MGI:6478231).
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted 4C Expression in DA neurons closely apposed to tangentially arranged nerve fibers.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory