Chd8 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:295033 Xu Q, et al., Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons. Mol Autism. 2018;9:65
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6477634
Gene symbol:	Chd8
Gene name:	chromodomain helicase DNA binding protein 8

Antibody:	anti-Chd8 (#A301-224A)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

3b CHD8 ©

3b Merge ©

Specimen 3b: postnatal day 3 (more

)
Note: Double labeled: green - Chd8; red - Rbfox3 (assay MGI:6477640)

Structure	Level	Pattern	Image	Note
TS27: neocortex	Present		3b Merge , 3b CHD8	Double labeling shows strong expression in neurons.

3c CHD8 ©

3c Merge ©

Specimen 3c: postnatal day 3 (more

)
Note: Double labeled: green - Chd8; red - Gfap (assay MGI:6477641)

Structure	Level	Pattern	Image	Note
TS27: hippocampus	Present		3c CHD8 , 3c Merge	Double labeling shows weak expression in astrocytes.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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