About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:278136 Hertz NT, et al., Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration. Neuron. 2019 Aug 7;103(3):412-422.e4
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6477598
Gene symbol: Ntrk1
Gene name: neurotrophic tyrosine kinase, receptor, type 1
Results
Specimen S4C: embryonic day 14.5 (more )
Note: Double labeled: aqua - Ntrk1; red - Rufy3 (assay MGI:6477597).
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present S4C right , S4C middle Partially coexpressed with Rufy3.
Specimen S4E Casp3+/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present S4E upper left
Specimen S4E Casp3-/-: embryonic day 14.5; Casp3tm1Flv/Casp3tm1Flv (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present S4E upper right Increased number in postive nerve bundles, compared with wild-type.
Specimen S4E Rufty3+/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present S4E lower left
Specimen S4E Rufty3-/-: embryonic day 14.5; Rufy3tm1b(EUCOMM)Hmgu/Rufy3tm1b(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present S4E lower right Increased number in postive nerve bundles, compared with wild-type. More severe defasciculation phenotype than in the Casp3-/- mutant.
Specimen S4G Casp3+/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cranial ganglion Present S4G upper left
Specimen S4G Casp3-/-: embryonic day 14.5; Casp3tm1Flv/Casp3tm1Flv (more )
Structure Level Pattern Image Note
TS22: cranial ganglion Present S4G lower left Similar pattern as in the wild-type.
Specimen S4G Rufty3+/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cranial ganglion Present S4G upper middle
Specimen S4G Rufty3-/-: embryonic day 14.5; Rufy3tm1b(EUCOMM)Hmgu/Rufy3tm1b(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS22: cranial ganglion Present S4G lower middle A pronounced defect in organization and fasciculation of positive axons was seen.
Specimen S4G Casp3-/- Rufty3+/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cranial ganglion Present S4G upper right Similar pattern as in the wild-type.
Specimen S4G Casp3-/- Rufty3-/-: embryonic day 14.5; Casp3tm1Flv/Casp3tm1Flv, Rufy3tm1b(EUCOMM)Hmgu/Rufy3tm1b(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS22: cranial ganglion Present S4G lower right A pronounced defect in organization and fasciculation of positive axons was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory