Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Gfi1tm2(GFP/cre/ERT2)Gan
Name:	growth factor independent 1 transcription repressor; targeted mutation 2, Lin Gan
MGI ID:	MGI:6477586
Synonyms:	Gfi1-GCE
Gene:	Gfi1  Location: Chr5:107864521-107873671 bp, - strand  Genetic Position: Chr5, 52.23 cM
Alliance:	Gfi1tm2(GFP/cre/ERT2)Gan page

Germline Transmission:	Earliest citation of germline transmission: J:297267
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEv or C57BL/6J

Allele Type:    Targeted (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Gfi1tm2(GFP/cre/ERT2)Gan expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gfi1 (MGI:103170)   Mutation details: The coding sequence for P2A-GFP/cre/ERT2 and a downstream FRT-flanked neomycin resistance cassette was inserted in-frame to the C-terminus resulting in bicistronic expression of the endogenous transcript and a tamoxifen-inducible cre recombinase with green fluorescent protein reporter. (J:297267) Inheritance:    Not Specified

Activity:	Tissue activity of this recombinase allele
Driver:	Gfi1 (mouse) Summary of all recombinase alleles driven by Gfi1. Alliance mouse Gfi1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gfi1 Mutation:	31 strains or lines available

Original:	J:297267 Tang Q, et al., Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis. 2019 Sep;57(9):e23304
All:	1 reference(s)