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Gene Expression Data
Assay Details
Assay
Reference: J:143513 Lathia JD, et al., Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation. J Neurosci. 2008 Dec 17;28(51):13978-84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6476680
Gene symbol: Tlr3
Gene name: toll-like receptor 3
Antibody: anti- TLR3 (CSA 790)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Strong 2A

Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present 2B

Specimen 2C: embryonic day 16.5 (more )
Note: Double labeled: green - Tlr3; red - Tubb3 (assay MGI:6476681).
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Strong 2C TLR3 , 2C Merge
TS24: cerebral cortex Present Regionally restricted 2C TLR3 , 2C Merge Expression is in the neural stem/progenitor region of the cerebral cortex and is weak in the outer regions.

Specimen S2A E13.5: embryonic day 13.5; Tlr3tm1Flv/Tlr3tm1Flv (more )
Note: The authors stated that expression in mutant embryos at E13.5 and E16.5 was absent but did not specify the age of the specimen shown in S2A. Both ages are annotated.
Structure Level Pattern Image Note
TS21: cerebral cortex Absent S2A

Specimen S2A E16.5: embryonic day 16.5; Tlr3tm1Flv/Tlr3tm1Flv (more )
Note: The authors stated that expression in mutant embryos at E13.5 and E16.5 was absent but did not specify the age of the specimen shown in S2A. Both ages are annotated.
Structure Level Pattern Image Note
TS24: cerebral cortex Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory