Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Ins1-INS/sfGFP)369Arvn
Name:	transgene insertion 369, Peter Arvan
MGI ID:	MGI:6474159
Synonyms:	hPro-CpepSfGFP
Transgene:	Tg(Ins1-INS/sfGFP)369Arvn  Location: unknown
Alliance:	Tg(Ins1-INS/sfGFP)369Arvn page

Strain of Origin:

C57BL/6J

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence, Reporter) Mutation:    Insertion   Tg(Ins1-INS/sfGFP)369Arvn expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human INS (3630) Ins1  (MGI:96572) Ins2  (MGI:96573)   Mutation details: The transgene contains a superfolder green fluorescent protein inserted in frame into the C-Peptide domain of human proinsulin. The fusion protein cDNA sequence is placed downstream of the murine insulin I (Ins1) promoter and is followed by a 2.5-kb human growth hormone (hGH) minigene that serves as an enhancer. (J:252954)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:252954 Zhu S, et al., Monitoring C-Peptide Storage and Secretion in Islet beta-Cells In Vitro and In Vivo. Diabetes. 2016 Mar;65(3):699-709
All:	1 reference(s)