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Gene Expression Data
Assay Details
Assay
Reference: J:175263 Kenchegowda D, et al., Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells. Dev Biol. 2011 Aug 1;356(1):5-18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6473848
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Detection system: Alexa Fluor 555
Results
Specimen 10A: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: eyelid skin Present 10A
Specimen 10B: postnatal day 21; Klf5tm1Jaw/Klf5tm1Jaw, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: eyelid skin Strong Regionally restricted 10B Expression significantly increased in palpebral epidermis and eyelid hair follicles.
TS28: hair follicle Strong Regionally restricted 10B Expression significantly increased in palpebral epidermis and eyelid hair follicles.
TS28: meibomian gland Present Regionally restricted 10B No difference in meibomian gland acinal or ductal epithelial cell proliferation.
Specimen 10C: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Weak Regionally restricted 10C Expression restricted to basal epithelium.
Specimen 10D: postnatal day 21; Klf5tm1Jaw/Klf5tm1Jaw, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 10D Expression also present in spinous cells layers.
Specimen 10E: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Weak Regionally restricted 10E Expression restricted to basal epithelium.
Specimen 10F: postnatal day 21; Klf5tm1Jaw/Klf5tm1Jaw, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Regionally restricted 10F Expression also present in spinous cells layers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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