Gene Expression Data
Assay Details
Assay
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Reference:
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J:296805
Chen S, et al., Runx2, osx, and dspp in tooth development. J Dent Res. 2009 Oct;88(10):904-9
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6473773
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Gene symbol:
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Sp7
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Gene name:
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Sp7 transcription factor 7
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Probe:
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Osx probe6
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Probe preparation:
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Antisense labelled with P32 RNA
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Results
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Specimen
S1C:
embryonic day 12.0
(more )
Specimen
S1C:
(close )
Genetic Background:
|
ICR
|
Age:
|
embryonic day 12.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: mandibular process mesenchyme |
Present |
Regionally restricted |
S1C
|
Expression in mesenchymal condensates of forming bones and teeth in developing maxillary and mandibular arches. Overall expression levels lower than that of Runx2.
|
TS20: maxillary process mesenchyme |
Present |
Regionally restricted |
S1C
|
Expression in mesenchymal condensates of forming bones and teeth in developing maxillary and mandibular arches. Overall expression levels lower than that of Runx2.
|
Specimen
1C:
embryonic day 14.0
(more )
Specimen
1C:
(close )
Genetic Background:
|
ICR
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: jaw mesenchyme |
Present |
Regionally restricted |
1C
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Co-expression with Runx2 in mesenchymal cells in alveolar bone,
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TS22: dental papilla |
Present |
Regionally restricted |
1C
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Co-expression with Runx2 in dental papilla and dental follicle.
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TS22: dental sac |
Present |
Regionally restricted |
1C
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Co-expression with Runx2 in dental papilla and dental follicle.
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TS22: tooth epithelium |
Trace |
|
1C
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Expression barely seen in dental epithelium.
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Specimen
1G:
embryonic day 16.0
(more )
Specimen
1G:
(close )
Genetic Background:
|
ICR
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
1K:
embryonic day 18.0
(more )
Specimen
1K:
(close )
Genetic Background:
|
ICR
|
Age:
|
embryonic day 18.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: jaw mesenchyme |
Present |
Regionally restricted |
1K
|
Expression in alveolar bone osteoblasts overlapped with Runx2 expression.
|
TS26: tooth mesenchyme |
Strong |
Regionally restricted |
1K
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Intense expression in odontoblasts and dental pulp cells.
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Specimen
S1G:
embryonic day 18.0
(more )
Specimen
S1G:
(close )
Genetic Background:
|
ICR
|
Age:
|
embryonic day 18.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: jaw mesenchyme |
Present |
Regionally restricted |
S1G
|
Expression in alveolar bone osteoblasts overlapped with Runx2 expression.
|
TS26: tooth mesenchyme |
Strong |
Regionally restricted |
S1G
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Intense expression in odontoblasts and dental pulp cells.
|
Specimen
S1K:
embryonic day 18.0
(more )
Specimen
S1K:
(close )
Genetic Background:
|
ICR
|
Age:
|
embryonic day 18.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: jaw mesenchyme |
Present |
Regionally restricted |
S1K
|
Expression in alveolar bone osteoblasts overlapped with Runx2 expression.
|
TS26: tooth mesenchyme |
Strong |
Regionally restricted |
S1K
|
Intense expression in odontoblasts and dental pulp cells.
|
Specimen
2C:
postnatal day 1
(more )
Specimen
2C:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 1
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: dental pulp |
Strong |
Regionally restricted |
2C
|
Intense expression in odontoblasts and dental pulp cells, in addition to osteoblasts.
|
TS27: jaw skeleton |
Strong |
Regionally restricted |
2C
|
Intense expression in odontoblasts and dental pulp cells, in addition to osteoblasts.
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Specimen
S2C:
postnatal day 1
(more )
Specimen
S2C:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 1
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Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: dental pulp |
Strong |
Regionally restricted |
S2C
|
Intense expression in odontoblasts and dental pulp cells, in addition to osteoblasts.
|
TS27: jaw skeleton |
Strong |
Regionally restricted |
S2C
|
Intense expression in odontoblasts and dental pulp cells, in addition to osteoblasts.
|
Specimen
2G:
postnatal day 5
(more )
Specimen
2G:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: dental pulp |
Strong |
Regionally restricted |
2G
|
Similar expression patterns to those seen at PN1. Expression more intense in odontoblasts.
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Specimen
S2G:
postnatal day 8
(more )
Specimen
S2G:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 8
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
2K:
postnatal day 10
(more )
Specimen
2K:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 10
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
S2K:
postnatal day 10
(more )
Specimen
S2K:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 10
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
S2O:
postnatal day 14
(more )
Specimen
S2O:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 14
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
S2S:
postnatal day 14
(more )
Specimen
S2S:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 14
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
|