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Gene Expression Data
Assay Details
Assay
Reference: J:236232 Wang W, et al., Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS Genet. 2016 Oct;12(10):e1006352
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6473206
Gene symbol: Smad1
Gene name: SMAD family member 1
Antibody: Anti-Phospho-Smad1/5/8
Detection system: Secondary antibody coupled to Alexa Fluor 594
Assay notes: The antibody recognized the phosphorylated Smad1/5/8 proteins.
Results
Specimen 3E Smad2fx/fx: postnatal day 0; Smad2tm2Rob/Smad2tm2Rob (more )
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 3E Smad2fx/fx Expression was detected in the growth plate.
Specimen 3E Smad2cko: postnatal day 0; Smad2tm2Rob/Smad2tm2Rob, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 3E Smad2cko No obvious change in expression was noted in the mutant compared with control.
Specimen 3E Smad3-/-: postnatal day 0; Smad3tm1Par/Smad3tm1Par (more )
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 3E Smad3-/- No obvious change in expression was noted in the mutant compared with control.
Specimen 3E Smad2cko;Smad3-/-: postnatal day 0; Smad2tm2Rob/Smad2tm2Rob, Smad3tm1Par/Smad3tm1Par, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 3E Smad2cko;Smad3-/- No obvious change in expression was noted in the double mutant compared with control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory