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Gene Expression Data
Assay Details
Assay
Reference: J:160254 Urness LD, et al., FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a. Dev Biol. 2010 Apr 15;340(2):595-604
Assay type: RNA in situ
MGI Accession ID: MGI:6473203
Gene symbol: Foxi3
Gene name: forkhead box I3
Probe: Foxi3 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3C: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: otic placode epithelium Present 3C Expression marks propective otic ectoderm.
Specimen 3C1: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: otic placode epithelium Present 3C1 Expression marks propective otic ectoderm.
Specimen 3D: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: otic placode Absent 3D Expression absent from dorsal ectoderm
Specimen 3D1: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: otic placode Absent 3D1 Expression absent from dorsal ectoderm
Specimen 4-6 somite not shown: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 4-6 somite stage
Structure Level Pattern Image Note
TS12: otic pre-placode Absent Expression eliminated from dorsal ectoderm.
Specimen 8-9 somite not shown: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 8-9 somite stage
Structure Level Pattern Image Note
TS13: otic placode Weak Expressipn only stlightly reduced in two 8-9 somite stage mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory