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Gene Expression Data
Assay Details
Assay
Reference: J:236232 Wang W, et al., Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS Genet. 2016 Oct;12(10):e1006352
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6473193
Gene symbol: Ihh
Gene name: Indian hedgehog
Antibody: anti-IHH (ab52919)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 3B Smad2fx/fx: postnatal day 0; Smad2tm2Rob/Smad2tm2Rob (more )
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 3C Smad2fx/fx , 3B Smad2fx/fx Expression was detected in prehypertrophic and hypertrophic zones.
Specimen 3B Smad2cko: postnatal day 0; Smad2tm2Rob/Smad2tm2Rob, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 3B Smad2cko , 3C Smad2cko Expression was detected in the prehypertrophic and hypertrophic zones, but unlike control was also detected in the resting zone.
Specimen 3B Smad3-/-: postnatal day 0; Smad3tm1Par/Smad3tm1Par (more )
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 3C Smad3-/- , 3B Smad3-/- Expression was detected in the prehypertrophic and hypertrophic zones, but unlike control was also detected in the resting zone.
Specimen 3B Smad2cko;Smad3-/-: postnatal day 0; Smad2tm2Rob/Smad2tm2Rob, Smad3tm1Par/Smad3tm1Par, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 3B Smad2cko;Smad3-/- , 3C Smad2cko;Smad3-/- Expression was detected in the prehypertrophic and hypertrophic zones, but unlike control was also detected in the resting zone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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