Aspm Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:205524 Fujimori A, et al., Disruption of Aspm causes microcephaly with abnormal neuronal differentiation. Brain Dev. 2014 Sep;36(8):661-9
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6473129
Gene symbol:	Aspm
Gene name:	abnormal spindle microtubule assembly

Antibody:	Aspm antibody
Detection system:	Secondary antibody coupled to Alexa Fluor 647

Results

Specimen S1C +/+ top: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: telencephalon	Present	Non-Uniform	S1_+/+ top	Expression is granular.
TS24: telencephalon subventricular zone	Present	Non-Uniform	S1_+/+ top	Expression is granular.
TS24: telencephalon ventricular layer	Present	Non-Uniform	S1_+/+ top	Expression is granular.

Specimen S1C +/- top: embryonic day 16.5; Aspm^tm1.2Kxi/Aspm⁺ (more

)

Structure	Level	Pattern	Image	Note
TS24: telencephalon	Weak	Non-Uniform	S1_+/- top	Expression is granular.
TS24: telencephalon subventricular zone	Weak	Non-Uniform	S1_+/- top	Expression is granular.
TS24: telencephalon ventricular layer	Weak	Non-Uniform	S1_+/- top	Expression is granular.

Specimen S1C -/- top: embryonic day 16.5; Aspm^tm1.2Kxi/Aspm^tm1.2Kxi (more

)

Structure	Level	Image
TS24: telencephalon	Absent	S1_-/- top
TS24: telencephalon subventricular zone	Absent	S1_-/- top
TS24: telencephalon ventricular layer	Absent	S1_-/- top

Specimen S1C +/+ bottom: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: telencephalon subventricular zone	Present	Non-Uniform	S1_+/+ bottom	Expression is granular.
TS24: telencephalon ventricular layer	Present	Non-Uniform	S1_+/+ bottom	Expression is granular.

Specimen S1C +/- bottom: embryonic day 16.5; Aspm^tm1.2Kxi/Aspm⁺ (more

)

Structure	Level	Pattern	Image	Note
TS24: telencephalon subventricular zone	Weak	Non-Uniform	S1_+/- bottom	Expression is granular.
TS24: telencephalon ventricular layer	Weak	Non-Uniform	S1_+/- bottom	Expression is granular.

Specimen S1C -/- bottom: embryonic day 16.5; Aspm^tm1.2Kxi/Aspm^tm1.2Kxi (more

)

Structure	Level	Pattern	Image	Note
TS24: telencephalon subventricular zone	Absent		S1_-/- botttom
TS24: telencephalon ventricular layer	Absent		S1_-/- botttom

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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