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Gene Expression Data
Assay Details
Assay
Reference: J:205524 Fujimori A, et al., Disruption of Aspm causes microcephaly with abnormal neuronal differentiation. Brain Dev. 2014 Sep;36(8):661-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6473123
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1 (AB31940)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 3 Aspm+/+: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cortical plate Present Regionally restricted 3_+/+ Tbr1 Expression is in the lower cortical plate.
TS24: cortical subplate Present 3_+/+ Tbr1

Specimen 3 +/-: embryonic day 16.5; Aspmtm1.2Kxi/Aspm+ (more )
Structure Level Pattern Image Note
TS24: cortical plate Present Regionally restricted 3_+/- Tbr1 Expression is in the lower cortical plate.
TS24: cortical subplate Present 3_+/- Tbr1

Specimen 3 -/-: embryonic day 16.5; Aspmtm1.2Kxi/Aspmtm1.2Kxi (more )
Structure Level Pattern Image Note
TS24: cortical plate Present Regionally restricted 3_-/- Tbr1 Expression is in the lower cortical plate.
TS24: cortical subplate Strong 3_-/- Tbr1 The immunoreactive area has increased in this mutant compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory