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Gene Expression Data
Assay Details
Assay
Reference: J:288446 Christians A, et al., Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies. Hum Mol Genet. 2020 May 8;29(7):1192-1204
Assay type: RNA in situ
MGI Accession ID: MGI:6473003
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Probe: Six2 probe10
Probe preparation: Antisense RNA
Results
Specimen S3A +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: ureter Present S3A Six2 Lifr+/+

Specimen S3A +/+ kidney: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: metanephros Present S3A Six2 Lifr+/+ inset

Specimen S3A -/-: embryonic day 18.5; Lifrtm1Imx/Lifrtm1Imx (more )
Structure Level Pattern Image Note
TS26: ureter Present S3A Six2 Lifr-/- Reduced expression compared with the wild-type.

Specimen S3A -/- kidney: embryonic day 18.5; Lifrtm1Imx/Lifrtm1Imx (more )
Structure Level Pattern Image Note
TS26: metanephros Present S3A Six2 Lifr-/- inset


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory